Cell Biology Antibodies 13

UGT1A6 Rabbit Polyclonal Antibody (CAB17166)

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SKU:
CAB17166
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
GNT1, UGT1, HLUGP, UDPGT, UGT1A, UGT1C, UGT1E, UGT1F, HLUGP1, UGT-1A, UGT-1C, UGT-1E, UGT-1F, UGT1.1, UGT1.3, UGT1.5, UGT1.6, UGT1A1, UGT1A3, UGT1A5, UGT1-01, UGT1-03, UGT1-05, UGT1-06, UGT1A6S, hUG-BR1, UDPGT 1-6, UGT1A6
Research Use:
Cell Biology
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Description

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UGT1A6 Antibody (CAB17166)

The UGT1A6 Antibody (CAB17166) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to UGT1A6, this antibody facilitates the detection and analysis of the enzyme in various cell types, making it a crucial component for investigations in pharmacology and toxicology research.

This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:UGT1A6 Antibody
SKU:CAB17166
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LLLK ESKY YTRK IYPV PYDQ EELK NRYQ SFGN NHFA ERSF LTAP QTEY RNNM IVIG LYFI NCQS LLQD RDTL NFFK ESKF DALF TDPA LPCG VILA EYLG LPSV YLFR GFPC SLEH TFSR SPDP VSYI PRCY TKFS DHMT FSQR VANF LVNL LEPY LFYC LFSK YEEL ASAV LKRD VDII TLYQ KVSV WLLR YDFV LEYP RPVM PN
Tested Applications:WB ELISA IF-P
Recommended Dilution:
WB1:500 - 1:2000
IF-P1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:GNT1, UGT1, HLUGP, UDPGT, UGT1A, UGT1C, UGT1E, UGT1F, HLUGP1, UGT-1A, UGT-1C, UGT-1E, UGT-1F, UGT1.1, UGT1.3, UGT1.5, UGT1.6, UGT1A1, UGT1A3, UGT1A5, UGT1-01, UGT1-03, UGT1-05, UGT1-06, UGT1A6S, hUG-BR1, UDPGT 1-6, UGT1A6
Positive Sample:A-431, HT-29, Mouse liver, Mouse kidney
Cellular Localization:Endoplasmic Reticulum Membrane, Microsome, Single-Pass Membrane Protein.
Calculated MW:61kDa
Observed MW:70kDa

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.

Purification MethodAffinity purification
Gene ID54578
RRIDAB_2772805
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using UGT1A6 Rabbit pAb (CAB17166) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunofluorescence analysis of paraffin-embedded rat liver using UGT1A6 Rabbit pAb (CAB17166) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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