Developmental Biology

TWIST2 Rabbit Polyclonal Antibody (CAB5599)

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SKU:
CAB5599
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
Reactivity:
Mouse, Rat
Synonyms:
AMS, FFDD3, BBRSAY, DERMO1, SETLSS, bHLHa39, TWIST2
Research Use:
Developmental Biology
Frequently bought together:

Description

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TWIST2 Antibody (CAB5599)

The TWIST2 Antibody (CAB5599) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for studies in molecular biology and cancer research.Twist2 is known for its involvement in epithelial-mesenchymal transition (EMT), a crucial process in embryonic development and tumor metastasis. By targeting Twist2, researchers can gain insights into the mechanisms underlying these processes and potential therapeutic targets for cancer treatment.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:TWIST2 Antibody
SKU:CAB5599
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MEEG SSSP VSPV DSLG TSEE ELER QPKR FGRK RRYS KKSS EDGS PTPG KRGK KGSP SAQS FEEL QSQR ILAN VRER QRTQ SLNE AFAA LRKI IPTL PSDK
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:AMS, FFDD3, BBRSAY, DERMO1, SETLSS, bHLHa39, TWIST2
Positive Sample:Rat uterus
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:18kDa
Observed MW:18kDa

The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found.

Purification MethodAffinity purification
Gene ID117581
RRIDAB_2766366
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Rat uterus, using TWIST2 Rabbit pAb (CAB5599) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 180s.
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