The TRPC1 Monoclonal Antibody (CAB4016) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using rabbit monoclonal technology, is highly reactive with human samples and is validated for use in a variety of applications, including Western blot and immunohistochemistry.TRPC1 plays a crucial role in various physiological processes, including calcium signaling, cell proliferation, and migration. Dysregulation of TRPC1 has been implicated in several diseases, such as neurological disorders, cardiovascular diseases, and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
TRPC1 Monoclonal Antibody
SKU:
CAB4016
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0884
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TRP1, HTRP-1, TRPC1
Positive Sample:
A549, PC-3, U-251MG, Mouse brain, Rat brain
Cellular Localization:
Membrane.
Calculated MW:
88kDa/91kDa
Observed MW:
130kDa
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
7220
RRID
AB_2863173
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using TRPC1 Rabbit mAb (CAB4016) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
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