ChIP Antibodies

TRMT1 Rabbit Polyclonal Antibody (CAB7116)

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SKU:
CAB7116
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse
Synonyms:
TRM1, MRT68, TRMT1
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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TRMT1 Antibody (CAB7116)

The TRMT1 Antibody (CAB7116) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is ideal for use in Western blot applications. TRMT1 plays a crucial role in maintaining the stability and functionality of tRNAs, essential for accurate protein synthesis in cells.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:TRMT1 Antibody
SKU:CAB7116
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:PSLL QLRS ALLH ADFR VSLS HACK NAVK TDAP ASAL WDIM RCWE KECP VKRE RLSE TSPA FRIL SVEP RLQA NFTI REDA NPSS RQRG LKRF QANP EANW GPRP RARP GGKA ADEA MEER RRLL QNKR KEPP EDVA QRAA RLKT FPCK RFKE GTCQ RGDQ CCYS HSPP TPRV SADA APDC PETS NQTP PGPG AAAG PGID
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:TRM1, MRT68, TRMT1
Positive Sample:MCF7, HL-60, Mouse heart
Cellular Localization:Nucleoplasm, Nucleus.
Calculated MW:72kDa
Observed MW:90kDa

This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome.

Purification MethodAffinity purification
Gene ID55621
RRIDAB_2767671
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using TRMT1 Rabbit pAb (CAB7116) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
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