Cell Biology Antibodies 10

TREX1 Rabbit Polyclonal Antibody (CAB6778)

(No reviews yet) Write a Review
SKU:
CAB6778
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CRV, AGS1, DRN3, HERNS, RVCLS, TREX1
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

TREX1 Antibody (CAB6778)

The TREX1 Antibody (CAB6778) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the TREX1 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in immunology, autoimmunity, and cancer research.TREX1, also known as DNase III, plays a crucial role in maintaining genomic stability by clearing out DNA fragments that can trigger inflammatory responses.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:TREX1 Antibody
SKU:CAB6778
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MGPG ARRQ GRIV QGRP EMCF CPPP TPLP PLRI LTLG THTP TPCS SPGS AAGT YPTM GSQA LPPG PMQT LIFF DMEA TGLP FSQP KVTE LCLL AVHR CALE SPPT SQGP PPTV PPPP RVVD KLSL CVAP GKAC SPAA SEIT GLST AVLA AHGR QCFD DNLA NLLL AFLR RQPQ PWCL VAHN GDRY DFPL LQAE LAML GLTS ALDG AFCV DSIT ALKA LERA SSPS EHGP RKSY SLGS IYTR LYGQ SPPD SHTA EGDV LALL SICQ WRPQ AL
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CRV, AGS1, DRN3, HERNS, RVCLS, TREX1
Positive Sample:HeLa, HT-29
Cellular Localization:Cytoplasm, Endoplasmic Reticulum Membrane, Nucleus, Peripheral Membrane Protein, Cytosol.
Calculated MW:33kDa
Observed MW:35kDa

This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID11277
RRIDAB_2767361
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using TREX1 Rabbit pAb (CAB6778) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunofluorescence analysis of MCF7 cells using TREX1 Rabbit pAb (CAB6778) at dilution of 1:50 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of PC-12 cells using TREX1 Rabbit pAb (CAB6778) at dilution of 1:50 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
View AllClose

0 Reviews

View AllClose

Related Products