Cell Death Antibodies 1

TNFRSF25 Rabbit Polyclonal Antibody (CAB14261)

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SKU:
CAB14261
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
Reactivity:
Human, Mouse, Rat
Synonyms:
DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, GEF720, WSL-LR, PLEKHG5, TNFRSF12, TNFRSF25
Research Use:
Cell Death
Frequently bought together:

Description

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TNFRSF25 Antibody (CAB14261)

The TNFRSF25 Antibody (CAB14261) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has a high degree of specificity for human samples and has been rigorously tested for use in Western blot applications. By binding to the TNFRSF25 protein, this antibody enables precise detection and analysis in a wide range of cell types, making it an invaluable asset for studies in immunology and cancer research.

This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:TNFRSF25 Antibody
SKU:CAB14261
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:QGGT RSPR CDCA GDFH KKIG LFCC RGCP AGHY LKAP CTEP CGNS TCLV CPQD TFLA WENH HNSE CARC QACD EQAS QVAL ENCS AVAD TRCG CKPG WFVE CQVS QCVS SSPF YCQP CLDC GALH RHTR LLCS RRDT DCGT CLPG FYEH GDGC VSCP TPPP SLAG AP
Tested Applications:WB ELISA IF-P
Recommended Dilution:
WB1:500 - 1:2000
IF-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, GEF720, WSL-LR, PLEKHG5, TNFRSF12, TNFRSF25
Positive Sample:Raji, HT-29, U-87MG, A-549
Cellular Localization:Cell Membrane, Secreted, Single-Pass Type I Membrane Protein.
Calculated MW:45kDa
Observed MW:60kDa

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.

Purification MethodAffinity purification
Gene ID8718
RRIDAB_2761123
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using TNFRSF25 Rabbit pAb (CAB14261) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Product ImageImmunofluorescence analysis of paraffin-embedded human colon carcinoma using TNFRSF25 Rabbit pAb (CAB14261) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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