Epigenetics & Nuclear Signaling Antibodies 5
Anti-TLE1 Antibody (CAB3528)
- SKU:
- CAB3528
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Antibody Name: | Anti-TLE1 Antibody |
Antibody SKU: | CAB3528 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human TLE1 |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Mouse lung, Mouse brain, Rat lung, Rat liver, HepG2, U-87MG |
Immunogen: | A synthesized peptide derived from human TLE1 |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 7088 |
Uniprot: | Q04724 |
Cellular Location: | |
Calculated MW: | 83kDa |
Observed MW: | 90KDa |
Synonyms: | ESG, ESG1, GRG1 |
Background: |
UniProt Protein Function: | Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. |
UniProt Code: | Q04724 |
NCBI GenInfo Identifier: | 29840816 |
NCBI Gene ID: | 7088 |
NCBI Accession: | Q04724.2 |
UniProt Secondary Accession: | Q04724,Q5T3G4, Q969V9, A8K495, |
UniProt Related Accession: | Q04724 |
Molecular Weight: | 83,201 Da |
NCBI Full Name: | Transducin-like enhancer protein 1 |
NCBI Synonym Full Names: | transducin like enhancer of split 1 |
NCBI Official Symbol: | TLE1 |
NCBI Official Synonym Symbols: | ESG; ESG1; GRG1 |
NCBI Protein Information: | transducin-like enhancer protein 1 |
UniProt Protein Name: | Transducin-like enhancer protein 1 |
UniProt Synonym Protein Names: | E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1 |
Protein Family: | Transducin-like enhancer protein |
UniProt Gene Name: | TLE1 |
UniProt Entry Name: | TLE1_HUMAN |
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