Cell Biology Antibodies 7

THPO Rabbit Polyclonal Antibody (CAB1825)

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SKU:
CAB1825
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
ML, TPO, MGDF, MKCSF, MPLLG, THCYT1, THPO
Research Use:
Cell Biology
Frequently bought together:

Description

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THPO Antibody (CAB1825)

The THPO Antibody (CAB1825) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to thrombopoietin, the antibody enables accurate detection and analysis of this important protein in various cell types.Thrombopoietin plays a crucial role in hematopoiesis, particularly in the regulation of megakaryocyte development and platelet formation.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:THPO Antibody
SKU:CAB1825
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:SPAP PACD LRVL SKLL RDSH VLHS RLSQ CPEV HPLP TPVL LPAV DFSL GEWK TQME ETKA QDIL GAVT LLLE GVMA ARGQ LGPT CLSS LLGQ LSGQ VRLL LGAL QSLL GTQG RTTA HKDP NAIF LSFQ HLLR GKVR FLML VGGS TLCV RRAP PTTA VPSR TSLV LTLN ELPN RTSG LLET NFTA SART TGSG LLKW QQGF RAKI PGLL NQTS RSLD QIPG YLNR IHEL LNGT RGLF PGPS RRTL GAPD ISSG TSDT GSLP PNLQ PGYS PSPT HPPT GQYT LFPL PPTL PTPV VQLH PLLP DPSA PTPT PTSP LLNT SYTH SQNL SQEG
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ML, TPO, MGDF, MKCSF, MPLLG, THCYT1, THPO
Positive Sample:SH-SY5Y, Rat kidney
Cellular Localization:Secreted.
Calculated MW:38kDa
Observed MW:38kDa

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

Purification MethodAffinity purification
Gene ID7066
RRIDAB_2763862
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using THPO Rabbit pAb (CAB1825) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
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