Cell Biology Antibodies 17
Anti-Thioredoxin 2 Antibody (CAB4424)
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- SKU:
- CAB4424
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Thioredoxin 2 Antibody |
| Antibody SKU: | CAB4424 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Thioredoxin 2 |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, BxPC-3, Jurkat, Mouse liver, Mouse brain, Mouse spleen, Rat liver, Rat kidney |
| Immunogen: | A synthesized peptide derived from human Thioredoxin 2 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 25828 |
| Uniprot: | Q99757 |
| Cellular Location: | |
| Calculated MW: | 12kDa |
| Observed MW: | 13KDa |
| Synonyms: | COXPD29, MT-TRX, MTRX, TRX2, TXN |
| Background: | This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | TXN2: Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity. Belongs to the thioredoxin family. |
| UniProt Protein Details: | Protein type:Oxidoreductase Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: cell soma; mitochondrion; mitochondrial matrix; dendrite; nucleolus Molecular Function:peptide-methionine-(S)-S-oxide reductase activity; protein complex binding; protein disulfide oxidoreductase activity; peptide-methionine (R)-S-oxide reductase activity Biological Process: response to drug; cellular response to nutrient levels; response to reactive oxygen species; cell redox homeostasis; response to hormone stimulus; response to glucose stimulus; response to hypoxia; response to axon injury; response to organic cyclic substance; glycerol ether metabolic process; response to nutrient |
| NCBI Summary: | This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99757 |
| NCBI GenInfo Identifier: | 20455529 |
| NCBI Gene ID: | 25828 |
| NCBI Accession: | Q99757.2 |
| UniProt Secondary Accession: | Q99757,Q5JZA0, Q6FH60, Q9UH29, |
| UniProt Related Accession: | Q99757 |
| Molecular Weight: | |
| NCBI Full Name: | Thioredoxin, mitochondrial |
| NCBI Synonym Full Names: | thioredoxin 2 |
| NCBI Official Symbol: | TXN2 |
| NCBI Official Synonym Symbols: | MTRX; TRX2; MT-TRX |
| NCBI Protein Information: | thioredoxin, mitochondrial; thioredoxin-2; mitochondrial thioredoxin |
| UniProt Protein Name: | Thioredoxin, mitochondrial |
| UniProt Synonym Protein Names: | Thioredoxin-2 |
| UniProt Gene Name: | TXN2 |
| UniProt Entry Name: | THIOM_HUMAN |
 | Western blot - Thioredoxin 2 Rabbit mAb (CAB4424) |
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