Immunology Antibodies 1

TEC Rabbit Polyclonal Antibody (CAB0189)

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SKU:
CAB0189
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
Reactivity:
Human, Mouse, Rat
Synonyms:
PSCTK4, Tec
Research Use:
Immunology
Frequently bought together:

Description

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TEC Antibody (CAB0189)

The TEC Antibody (CAB0189) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the TEC protein, this antibody enables detection and analysis in a variety of cell types, making it an ideal choice for studies in immunology, cancer research, and beyond.TEC is known to play a critical role in various cellular processes, including immune cell activation and signaling. Its involvement in signaling pathways related to cell growth, differentiation, and survival makes it an intriguing target for further investigation in the fields of immunology and cancer biology.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:TEC Antibody
SKU:CAB0189
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MNFN TILE EILI KRSQ QKKK TSPL NYKE RLFV LTKS MLTY YEGR AEKK YRKG FIDV SKIK CVEI VKND DGVI PCQN KYPF QVVH DANT LYIF APSP QSRD LWVK KLKE EIKN NNNI MIKY HPKF WTDG SYQC CRQT EKLA PGCE KYNL FESS IRKA LPPA PETK KRRP PPPI PLEE EDNS EEIV VAMY DFQA AEGH DLRL ERGQ EYLI LEKN DVHW WRAR DKYG NEGY IPSN YVTG KKSN NLDQ YEWY CRNM NRSK AEQL LRSE DKEG GFMV RDSS QPGL
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:5000
IF/ICC1:50 - 1:200
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PSCTK4, Tec
Positive Sample:Jurkat, Mouse liver, Mouse spleen, Mouse kidney, Rat liver
Cellular Localization:Cell Membrane, Cytoplasm, Peripheral Membrane Protein, Cytoskeleton.
Calculated MW:74kDa
Observed MW:68kDa

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Purification MethodAffinity purification
Gene ID7006
RRIDAB_2757009
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Tec Rabbit pAb (CAB0189) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. DeTection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human colon using Tec Rabbit pAb (CAB0189) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse spleen using Tec Rabbit pAb (CAB0189) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat spleen using Tec Rabbit pAb (CAB0189) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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