Signal Transduction Antibodies 3

TCN1 Rabbit Polyclonal Antibody (CAB6414)

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SKU:
CAB6414
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse, Rat
Synonyms:
HC, TC1, TCI, TC-1, TCN1
Research Use:
Signal Transduction
Frequently bought together:

Description

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TCN1 Antibody (CAB6414)

The TCN1 Antibody (CAB6414) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is produced in rabbits and has been validated for Western blot applications, making it a reliable choice for detecting and analyzing Transcobalamin-1 in various samples.Transcobalamin-1, also known as TCN1, is essential for the uptake and transport of vitamin B12, which is crucial for multiple biological processes, including DNA synthesis and nerve function. Dysregulation of Transcobalamin-1 has been linked to vitamin B12 deficiency and various health conditions, making it a promising target for further investigation in the fields of nutrition, metabolism, and neurology.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:TCN1 Antibody
SKU:CAB6414
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:EICE VSEE NYIR LKPL LNTM IQSN YNRG TSAV NVVL SLKL VGIQ IQTL MQKM IQQI KYNV KSRL SDVS SGEL ALII LALG VCRN AEEN LIYD YHLI DKLE NKFQ AEIE NMEA HNGT PLTN YYQL SLDV LALC LFNG NYST AEVV NHFT PENK NYYF GSQF SVDT GAMA VLAL TCVK KSLI NGQI KADE GSLK NISI YTKS LVEK ILSE KKEN GLIG NTFS TGEA MQAL FVSS DYYN ENDW NCQQ TLNT VLTE ISQG A
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HC, TC1, TCI, TC-1, TCN1
Positive Sample:BT-474, HT-29
Cellular Localization:Secreted.
Calculated MW:48kDa
Observed MW:48kDa

This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.

Purification MethodAffinity purification
Gene ID6947
RRIDAB_2767016
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using TCN1 Rabbit pAb (CAB6414) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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