Cell Biology Antibodies 13

TBCC Rabbit Polyclonal Antibody (CAB17537)

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SKU:
CAB17537
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CFC, TBCC
Research Use:
Cell Biology
Frequently bought together:

Description

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TBCC Antibody (CAB17537)

The TBCC Antibody (CAB17537) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications.TBCC, also known as Tubulin-specific Chaperone C, is essential for the proper assembly and function of microtubules, which are involved in various cellular functions such as cell division, intracellular transport, and cell shape maintenance.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:TBCC Antibody
SKU:CAB17537
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MESV SCSA AAVR TGDM ESQR DLSL VPER LQRR EQER QLEV ERRK QKRQ NQEV EKEN SHFF VATF ARER AAVE ELLE RAES VERL EEAA SRLQ GLQK LIND SVFF LAAY DLRQ GQEA LARL QAAL AERR RGLQ PKKR FAFK TRGK DAAS STKV DAAP GIPP AVES IQDS PLPK KAEG DLGP SWVC GFSN LESQ VLEK RASE LHQR DVLL TELS NCTV RLYG NPNT LRLT KAHS CKLL CGPV STSV FLED CSDC VLAV ACQQ LRIH STKD TRIF LQVT SRAI VEDC SGIQ FAPY TWSY PEID KDFE SSGL DRSK NNWN DVDD FNWL ARDM ASPN WSIL PEEE RNIQ WD
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CFC, TBCC
Positive Sample:HeLa, U-87MG, Mouse testis, Mouse brain, Mouse heart, Rat brain, Rat testis, Rat lung
Cellular Localization:Cytoplasm, Cytoskeleton, Cytosol.
Calculated MW:39kDa
Observed MW:39kDa

Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

Purification MethodAffinity purification
Gene ID6903
RRIDAB_2772535
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using TBCC Rabbit pAb (CAB17537) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunofluorescence analysis of C6 cells using TBCC Rabbit pAb (CAB17537) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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