Name: Anti-SUZ12 Antibody (CAB4348)
Brand: Epigenetics & Nuclear Signaling Antibodies 5
SKU: CAB4348
Availability: OutOfStock

Antibody Name:	Anti-SUZ12 Antibody
Antibody SKU:	CAB4348
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthesized peptide derived from human SUZ12

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	HeLa, HT-29, MCF7, Mouse lung, Mouse brain, Rat lung

Immunogen:	A synthesized peptide derived from human SUZ12
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	23512
Uniprot:	Q15022
Cellular Location:
Calculated MW:	83kDa
Observed MW:	83KDa

Synonyms:	CHET9, JJAZ1
Background:	This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 2009]

UniProt Protein Function:	SUZ12: a zinc finger protein. A breakpoint translocation of the cognate gene with JAZF1 has been reported in endometrial stromal sarcoma.
UniProt Protein Details:	Protein type:Transcription factor; Oncoprotein; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: nucleoplasm; ESC/E(Z) complex; sex chromatin; nucleolus; nucleus Molecular Function:histone methyltransferase activity; protein binding; sequence-specific DNA binding; RNA binding; metal ion binding; chromatin binding; methylated histone residue binding Biological Process: histone methylation; negative regulation of cell differentiation; transcription, DNA-dependent; negative regulation of gene expression, epigenetic; positive regulation of cell proliferation; histone ubiquitination; gene expression; negative regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic
NCBI Summary:	This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 2009]
UniProt Code:	Q15022
NCBI GenInfo Identifier:	116242808
NCBI Gene ID:	23512
NCBI Accession:	Q15022.3
UniProt Secondary Accession:	Q15022,Q96BD9,
UniProt Related Accession:	Q15022
Molecular Weight:	739
NCBI Full Name:	Polycomb protein SUZ12
NCBI Synonym Full Names:	SUZ12 polycomb repressive complex 2 subunit
NCBI Official Symbol:	SUZ12
NCBI Official Synonym Symbols:	CHET9; JJAZ1
NCBI Protein Information:	polycomb protein SUZ12; chET 9 protein; joined to JAZF1 protein; suppressor of zeste 12 homolog; suppressor of zeste 12 protein homolog; chromatin precipitated E2F target 9 protein
UniProt Protein Name:	Polycomb protein SUZ12
UniProt Synonym Protein Names:	Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homolog
Protein Family:	Polycomb protein
UniProt Gene Name:	SUZ12
UniProt Entry Name:	SUZ12_HUMAN