Immunology Antibodies 3

STAT3 Rabbit Polyclonal Antibody (CAB16975)

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SKU:
CAB16975
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
Reactivity:
Human, Mouse, Rat
Synonyms:
APRF, HIES, ADMIO, ADMIO1, STAT3
Research Use:
Immunology
Frequently bought together:

Description

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STAT3 Antibody (CAB16975)

The STAT3 Antibody (CAB16975) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in Western blot applications. By binding to STAT3, this antibody allows for the detection and analysis of this important transcription factor in various cell types.STAT3 is a critical regulator of cell growth, survival, and differentiation, with implications in cancer, inflammation, and immune response.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:STAT3 Antibody
SKU:CAB16975
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:NHPT AAVV TEKQ QMLE QHLQ DVRK RVQD LEQK MKVV ENLQ DDFD FNYK TLKS QGDM QDLN GNNQ SVTR QKMQ QLEQ MLTA LDQM RRSI VSEL AGLL SAME YVQK TLTD EELA DWKR RQQI ACIG GPPN ICLD RLEN WITS LAES QLQT RQQI KKLE ELQQ KVSY KGDP IVQH RPML EERI VELF RNLM KSAF VVER QPCM PMHP DRPL VIKT GVQF TTKV RLLV KFPE LNYQ LKIK VCID KDSG DVAA LRGS RKFN ILGT NTKV MNME ESNN GSLS AEFK HLTL REQR CGNG GRAN CDAS LIVT EELH LITF ETEV YHQG LKID LETH SLPV VVIS NICQ MPNA WASI LWYN MLTN NPKN VNFF TKPP IGTW DQVA EVLS WQFS STTK RGLS IEQL TTLA EKLL GPGV NYSG CQIT WAKF CKEN MAGK GFSF WVWL DNII DLVK KYIL ALWN EGYI MGFI SKER ERAI LSTK PPGT FLLR FSES SKEG GVTF TWVE KDIS GKTQ IQSV EPYT KQQL NNMS FAEI IMGY KIMD ATNI LVSP LVYL YPDI PKEE AFGK YCRP ESQE HPEA DPGS AAPY LKTK FICV TP
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:APRF, HIES, ADMIO, ADMIO1, STAT3
Positive Sample:A-549, Rat kidney
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:88kDa
Observed MW:79kDa

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. This gene also plays a role in regulating host response to viral and bacterial infections. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome.

Purification MethodAffinity purification
Gene ID6774
RRIDAB_2772423
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from A-549 cells, using STAT3 Rabbit pAb (CAB16975) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageWestern blot analysis of lysates from Rat kidney , using STAT3 Rabbit pAb (CAB16975) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
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