Cell Biology Antibodies 12

SNX15 Rabbit Polyclonal Antibody (CAB9158)

(No reviews yet) Write a Review
SKU:
CAB9158
Product Type:
Antibody
Applications:
WB
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
HSAF001435, SNX15
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

SNX15 Antibody (CAB9158)

The SNX15 Antibody (CAB9158) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for use in various research applications such as Western blotting.SNX15 is implicated in endosomal sorting and recycling processes, playing a key role in maintaining cellular homeostasis and regulating cellular signaling pathways. Dysfunction of SNX15 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:SNX15 Antibody
SKU:CAB9158
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSRQ AKDD FLRH YTVS DPRT HPKG YTEY KVTA QFIS KKDP EDVK EVVV WKRY SDFR KLHG DLAY THRN LFRR LEEF PAFP RAQV FGRF EASV IEER RKGA EDLL RFTV HIPA LNNS PQLK EFFR GGEV TRPL EVSR DLHI LPPP LIPT PPPD DPRL SQLL PAER RGLE ELEV PVDP PPSS PAQE ALDL LFNC ESTE EASG SPAR GPLT EAEL ALFD PFSK EEGA APSP THVA ELAT MEVE SARL DQEP WEPG GQEE EEDG EGGP TPAY LSQA TELI TQAL RDEK AGAY AAAL QGYR DGVH VLLQ GVPS DPLP ARQE GVKK KAAE YLKR AEEI LRLH LSQL PP
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HSAF001435, SNX15
Positive Sample:U-87MG, HepG2, Jurkat, Raji, Mouse spleen
Cellular Localization:Cytoplasm, Cytoplasmic Side, Cytoplasmic Vesicle Membrane, Membrane, Peripheral Membrane Protein.
Calculated MW:38kDa
Observed MW:50kDa

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Purification MethodAffinity purification
Gene ID29907
RRIDAB_2772333
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SNX15 Rabbit pAb (CAB9158) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunofluorescence analysis of C6 cells using SNX15 Rabbit pAb (CAB9158) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of L929 cells using SNX15 Rabbit pAb (CAB9158) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
View AllClose

0 Reviews

View AllClose

Related Products