Cell Biology Antibodies 15

SIGLEC15 Rabbit Polyclonal Antibody (CAB18660)

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SKU:
CAB18660
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Rat
Synonyms:
CD33L3, HsT1361, SIGLEC-15, Siglec-15
Research Use:
Cell Biology
Frequently bought together:

Description

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SIGLEC15 Antibody (CAB18660)

The SIGLEC15 Antibody (CAB18660) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody is highly specific and reacts with human samples, making it ideal for Western blot applications to detect and analyze Siglec15 expression in various cell types.Siglec15 is a member of the Siglec family of proteins, which are known to play a critical role in immune responses and inflammation regulation. Research has shown that Siglec15 is upregulated in certain types of cancer, suggesting a role in tumor immune evasion.

This antibody is validated for use in WB, IHC-P, ELISA, IF-P applications and has demonstrated reactivity against Human, Rat samples.

Product Name:SIGLEC15 Antibody
SKU:CAB18660
Size:20μL, 100μL
Reactivity:Human, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:FVRT KIDT TENL LNTE VHSS PAQR WSMQ VPPE VSAE AGDA AVLP CTFT HPHR HYDG PLTA IWRA GEPY AGPQ VFRC AAAR GSEL CQTA LSLH GRFR LLGN PRRN DLSL RVER LALA DDRR YFCR VEFA GDVH DRYE SRHG VRLH VTAA PRIV NISV LPSP AHAF RALC TAEG EPPP ALAW SGPA LGNS LAAV RSPR EGHG HLVT AELP ALTH DGRY TCTA ANSL GRSE ASVY LFRF HGAS GAST
Tested Applications:WB IHC-P ELISA IF-P
Recommended Dilution:
WB1:500 - 1:1000
IF-P1:50 - 1:200
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CD33L3, HsT1361, SIGLEC-15, Siglec-15
Positive Sample:HUVEC, Rat brain
Cellular Localization:Plasma Membrane.
Calculated MW:36kDa
Observed MW:36kDa

Predicted to be involved in regulation of actin cytoskeleton organization; regulation of bone resorption; and regulation of osteoclast development. Predicted to be integral component of membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane.

Purification MethodAffinity purification
Gene ID284266
RRIDAB_2862397
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Siglec-15 Rabbit pAb (CAB18660) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human spleen using Siglec-15 Rabbit pAb (CAB18660) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M Tris/EDTA Buffer (pH 9.0) prior to IHC staining.
Product ImageImmunofluorescence analysis of paraffin-embedded human spleen using Siglec-15 Rabbit pAb (CAB18660) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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