Cell Biology Antibodies 15

SEC62 Rabbit Polyclonal Antibody (CAB18589)

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SKU:
CAB18589
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
HTP1, TP-1, Dtrp1, TLOC1, SEC62
Research Use:
Cell Biology
Frequently bought together:

Description

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SEC62 Antibody (CAB18589)

The SEC62 Antibody (CAB18589) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody is highly specific and reactive with human samples, making it an ideal choice for use in Western blot applications.Sec62 is essential for protein translocation into the ER and plays a crucial role in maintaining cellular homeostasis. Dysregulation of Sec62 has been implicated in various diseases, including cancer and neurodegenerative disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:SEC62 Antibody
SKU:CAB18589
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:GRHH FWFL PNLT ADVG FIDS FRPL YTHE YKGP KADL KKDE KSET KKQQ KSDS EEKS DSEK KEDE EGKV GPGN HGTE GSGG ERHS DTDS DRRE DDRS QHSS GNGN DFEM ITKE ELEQ QTDG DCEE DEEE ENDG ETPK SSHE KS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HTP1, TP-1, Dtrp1, TLOC1, SEC62
Positive Sample:Hep G2, NIH/3T3, C6
Cellular Localization:Endoplasmic Reticulum, Rough Endoplasmic Reticulum.
Calculated MW:46kDa
Observed MW:50kDa

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Purification MethodAffinity purification
Gene ID7095
RRIDAB_2862349
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using SEC62 Rabbit pAb (CAB18589) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates / proteins: 25 μg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 45s.
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