Cell Biology Antibodies 5

Sec23B Rabbit Polyclonal Antibody (CAB15131)

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SKU:
CAB15131
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CWS7, CDAII, CDAN2, CDA-II, HEMPAS, hSec23B, Sec23B
Research Use:
Cell Biology
Frequently bought together:

Description

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Sec23B Antibody (CAB15131)

The Sec23B Antibody (CAB15131) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to SEC23B protein, this antibody enables precise detection and analysis in a variety of cell types, making it well-suited for investigations in cell biology and protein trafficking.SEC23B is essential for the proper functioning of the secretory pathway, playing a critical role in maintaining cellular homeostasis and ensuring the correct transport of proteins within cells.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Sec23B Antibody
SKU:CAB15131
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:SLQM SLSL LPPD ALVG LITF GRMV QVHE LSCE GISK SYVF RGTK DLTA KQIQ DMLG LTKP AMPM QQAR PAQP QEHP FASS RFLQ PVHK IDMN LTDL LGEL Q
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CWS7, CDAII, CDAN2, CDA-II, HEMPAS, hSec23B, Sec23B
Positive Sample:HeLa, HepG2, Raji
Cellular Localization:Endoplasmic Reticulum Membrane, Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Golgi Apparatus Membrane.
Calculated MW:86kDa
Observed MW:86kDa

The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene.

Purification MethodAffinity purification
Gene ID10483
RRIDAB_2762017
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Sec23B Rabbit pAb (CAB15131) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunofluorescence analysis of C6 cells using Sec23B Rabbit pAb (CAB15131) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of U-2 OS cells using Sec23B Rabbit pAb (CAB15131) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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