Signal Transduction Antibodies 1

SCN2A Rabbit Polyclonal Antibody (CAB10574)

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SKU:
CAB10574
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Synonyms:
EA9, HBA, NAC2, BFIC3, BFIS3, BFNIS, DEE11, HBSCI, EIEE11, HBSCII, Nav1.2, SCN2A1, SCN2A2, Na(v)1.2, SCN2A
Research Use:
Signal Transduction
Frequently bought together:

Description

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SCN2A Antibody (CAB10574)

The SCN2A Antibody (CAB10574) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blot and immunohistochemistry.SCN2A is known to be involved in various neurological disorders, including epilepsy and autism spectrum disorders. Research on this gene and its protein product is essential for understanding the underlying mechanisms of these conditions and developing potential therapeutic interventions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:SCN2A Antibody
SKU:CAB10574
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:RNKC LQWP PDNS SFEI NITS FFNN SLDG NGTT FNRT VSIF NWDE YIED KSHF YFLE GQND ALLC GNSS DAGQ CPEG YICV KAGR NPNY GYTS FDTF SWAF LSLF RLMT QDFW ENLY QLTL RAAG KTY
Tested Applications:WB ELISA
Recommended Dilution:
WB1:1000 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:EA9, HBA, NAC2, BFIC3, BFIS3, BFNIS, DEE11, HBSCI, EIEE11, HBSCII, Nav1.2, SCN2A1, SCN2A2, Na(v)1.2, SCN2A
Positive Sample:U-87MG, K-562
Cellular Localization:Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:228kDa
Observed MW:250kDa

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels function in the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. Allelic variants of this gene are associated with seizure disorders and autism spectrum disorder. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID6326
RRIDAB_2758116
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SCN2A Rabbit pAb (CAB10574) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
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