Cell Death Antibodies 1

S100A8 Rabbit Polyclonal Antibody (CAB1688)

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SKU:
CAB1688
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
Reactivity:
Human, Mouse, Rat
Synonyms:
P8, MIF, NIF, CAGA, CFAG, CGLA, L1Ag, MRP8, CP-10, MA387, 60B8AG, S100-A8, S100A8
Research Use:
Cell Death
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

S100A8 Antibody (CAB1688)

The S100A8 Antibody (CAB1688) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications.S100-A8 is a key player in the regulation of inflammatory processes and has been implicated in various disease states, including cancer, autoimmune disorders, and chronic inflammatory conditions.

This antibody is validated for use in WB, IHC-P, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:S100A8 Antibody
SKU:CAB1688
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MLTE LEKA LNSI IDVY HKYS LIKG NFHA VYRD DLKK LLET ECPQ YIRK KGAD VWFK ELDI NTDG AVNF QEFL ILVI KMGV AAHK KSHE ESHK E
Tested Applications:WB IHC-P ELISA IF-P
Recommended Dilution:
WB1:500 - 1:1000
IF-P1:50 - 1:100
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:P8, MIF, NIF, CAGA, CFAG, CGLA, L1Ag, MRP8, CP-10, MA387, 60B8AG, S100-A8, S100A8
Positive Sample:THP-1
Cellular Localization:Cell Membrane, Cytoplasm, Peripheral Membrane Protein, Secreted, Cytoskeleton.
Calculated MW:11kDa
Observed MW:11kDa

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID6279
RRIDAB_2763740
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from THP-1 cells, using S100A8 Rabbit pAb (CAB1688) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Extranodal NK-T-cell lymphoma using S100A8 Rabbit pAb (CAB1688) at dilution of 1:50 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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