Developmental Biology

RUFY3 Rabbit Polyclonal Antibody (CAB12896)

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SKU:
CAB12896
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
Reactivity:
Mouse, Rat
Synonyms:
RIPX, SINGAR1, ZFYVE30, RUFY3
Research Use:
Developmental Biology
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Description

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RUFY3 Antibody (CAB12896)

The RUFY3 Antibody (CAB12896) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has been rigorously validated for use in various applications, including Western blot and immunofluorescence.Rufy3, also known as RUN and FYVE domain-containing protein 3, is involved in the regulation of cell migration, cytoskeletal organization, and vesicle transport.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:RUFY3 Antibody
SKU:CAB12896
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSAL TPPT DMPT PTTD KITQ AAME TIYL CKFR VSMD GEWL CLRE LDDI SLTP DPEP THED PNYL M
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:RIPX, SINGAR1, ZFYVE30, RUFY3
Positive Sample:Mouse brain, Rat brain
Cellular Localization:Cell Projection, Cytoplasm, Endomembrane System, Perikaryon, Filopodium, Growth Cone, Invadopodium, Lamellipodium.
Calculated MW:53kDa
Observed MW:56kDa

This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID22902
RRIDAB_2759740
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using RUFY3 Rabbit pAb (CAB12896) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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