Cell Death Antibodies 2

RNF34 Rabbit Polyclonal Antibody (CAB8517)

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SKU:
CAB8517
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
Antibody Type:
Polyclonal Antibody
Synonyms:
RFI, RIF, RIFF, hRFI, CARP1, CARP-1, RNF34
Research Use:
Cell Death
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

RNF34 Antibody (CAB8517)

The RNF34 Antibody (CAB8517) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to RNF34, this antibody allows for the detection and analysis of the protein in various cellular contexts, making it an essential component for studies in immunology and cancer research.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:RNF34 Antibody
SKU:CAB8517
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MKAG ATSM WASC CGLL NEVM GTGA VRGQ QSAF AGAT GPFR FTPN PEFS TYPP AATE GPNI VCKA CGLS FSVF RKKH VCCD CKKD FCSV CSVL QENL RRCS TCHL LQET AFQR PQLM RLKV KDLR QYLI LRNI PIDT CREK EDLV DLVL CHHG LGSE DDMD TSSL NSSR SQTS SFFT RSFF SNYT APSA TMSS FQGE LMDG DQTS RSGV PAQV QSEI TSAN
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:RFI, RIF, RIFF, hRFI, CARP1, CARP-1, RNF34
Positive Sample:U-251MG, LO2, HeLa, BT-474
Cellular Localization:Cell Membrane, Cytoplasm, Endomembrane System, Nucleus, Nucleus Speckle, Peripheral Membrane Protein, Cytosol.
Calculated MW:42kDa
Observed MW:42kDa

The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.

Purification MethodAffinity purification
Gene ID80196
RRIDAB_2772049
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using RNF34 Rabbit pAb (CAB8517) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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