Cell Biology Antibodies 14

RELN Rabbit Polyclonal Antibody (CAB17936)

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SKU:
CAB17936
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
RL, ETL7, LIS2, PRO1598, RELN
Research Use:
Cell Biology
Frequently bought together:

Description

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RELN Antibody (CAB17936)

The RELN Antibody (CAB17936) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific and sensitive to RELN, a protein involved in neuronal migration and positioning during brain development.With its reactivity towards human samples, the RELN Polyclonal Antibody is suitable for Western blot applications, allowing for accurate detection and quantification of RELN expression levels in different cell types.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:RELN Antibody
SKU:CAB17936
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:KIST KNPD FLKD DFEG QLES DRFL LMSG GKPS RKCG ILSS GNNL FFNE DGLR MLMT RDLD LSHA RFVQ FFMR LGCG KGVP DPRS QPVL LQYS LNGG LSWS LLQE FLFS NSSN VGRY IALE IPLK ARSG STRL RWWQ PSEN GHFY SPWV IDQI LIGG NISG N
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:RL, ETL7, LIS2, PRO1598, RELN
Positive Sample:U-87MG, C6, LO2, HepG2
Cellular Localization:Cytoplasm, Dendrite, Extracellular Region, Extracellular Space, Neuron Projection, Plasma Membrane, Reelin Complex.
Calculated MW:388kDa
Observed MW:180kDa/388kDa

This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined.

Purification MethodAffinity purification
Gene ID5649
RRIDAB_2771981
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using RELN Rabbit pAb (CAB17936) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
Product ImageWestern blot analysis of lysates from HepG2 cells, using RELN Rabbit pAb (CAB17936) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 3min.
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