Cell Cycle Antibodies 1

RBBP8 Rabbit Polyclonal Antibody (CAB10201)

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SKU:
CAB10201
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle
Synonyms:
RIM, COM1, CTIP, JWDS, SAE2, JAWAD, SCKL2, RBBP8
Research Use:
Cell Cycle
Frequently bought together:

Description

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RBBP8 Antibody (CAB10201)

The RBBP8 Antibody (CAB10201) is a high-quality antibody developed for reliable detection and analysis of target proteins. CtIP plays a crucial role in DNA repair and cell cycle regulation, making it a key player in maintaining genomic stability. This antibody, generated in rabbits, has high specificity and sensitivity for detecting RBBP8 in human samples, making it ideal for Western blot applications.By targeting the RBBP8 protein, this antibody allows for the detection and analysis of CtIP levels in various cell types, providing valuable insights into DNA repair mechanisms and cell cycle control.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.

Product Name:RBBP8 Antibody
SKU:CAB10201
Size:20μL, 100μL
Reactivity:Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:VSFE NIQW SIDP GADL SQYK MDVT VIDT KDGS QSKL GGET VDMD CTLV SETV LLKM KKQE QKGE KSSN EERK MNDS LEDM FDRT THEE YESC LADS FSQA ADEE EELS TATK KLHT HGDK QDKV KQKA FVEP YFKG DERE TSLQ NFPH IEVV RKKE ERRK LLGH TCKE CEIY YADM PAEE REKK LASC SRHR FRYI PPNT PENF WEVG FPST QTCM ERGY IKED LDPC PRPK RRQP YNAI FSPK GKEQ KT
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:RIM, COM1, CTIP, JWDS, SAE2, JAWAD, SCKL2, RBBP8
Positive Sample:Rat thymus
Cellular Localization:Nucleus.
Calculated MW:102kDa
Observed MW:110kDa

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.

Purification MethodAffinity purification
Gene ID5932
RRIDAB_2757723
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Rat thymus, using RBBP8 Rabbit pAb (CAB10201) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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