Autophagy Antibodies

RAB1B Rabbit Polyclonal Antibody (CAB7514)

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SKU:
CAB7514
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Autophagy
Reactivity:
Human, Mouse
Synonyms:
RAB1B
Research Use:
Autophagy
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Description

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RAB1B Antibody (CAB7514)

The RAB1B Antibody (CAB7514) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting Rab1B in human samples, making it an ideal choice for Western blot applications.Rab1B is a member of the Ras family of small GTPases and is involved in the transport of proteins between the endoplasmic reticulum (ER) and the Golgi apparatus. Dysregulation of Rab1B has been linked to various diseases including cancer, neurodegenerative disorders, and infectious diseases.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:RAB1B Antibody
SKU:CAB7514
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:YLFK LLLI GDSG VGKS CLLL RFAD DTYT ESYI STIG VDFK IRTI ELDG KTIK LQIW DTAG QERF RTIT SSYY RGAH GIIV VYDV TDQE SYAN VKQW LQEI DRYA SENV NKLL VGNK SDLT TKKV VDNT TAKE FADS LGIP FLET SAKN ATNV EQAF MTMA AEIK KRMG PGAA SGGE RPNL KIDS TPVK PAGG GCC
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:RAB1B
Positive Sample:HeLa
Cellular Localization:Cytoplasm, Cytoplasmic Side, Lipid-Anchor, Membrane, Preautophagosomal Structure Membrane.
Calculated MW:22kDa
Observed MW:22kDa

Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).

Purification MethodAffinity purification
Gene ID81876
RRIDAB_2768044
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and RAB1B knockout (KO) HeLa cells using [KO Validated] RAB1B Rabbit pAb RAB1B Rabbit pAb (CAB7514) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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