Autophagy Antibodies

PTPN22 Rabbit Polyclonal Antibody (CAB1406)

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SKU:
CAB1406
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Autophagy
Reactivity:
Human, Mouse, Rat
Synonyms:
LYP, PEP, LYP1, LYP2, PTPN8, PTPN22.5, PTPN22.6, PTPN22
Research Use:
Autophagy
Frequently bought together:

Description

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PTPN22 Antibody (CAB1406)

The PTPN22 Antibody (CAB1406) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PTPN22 protein, it allows for precise detection and analysis in various cell types, making it an essential component in immunology and autoimmune disease research.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PTPN22 Antibody
SKU:CAB1406
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MDQR EILQ KFLD EAQS KKIT KEEF ANEF LKLK RQST KYKA DKTY PTTV AEKP KNIK KNRY KDIL PYDY SRVE LSLI TSDE DSSY INAN FI
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:LYP, PEP, LYP1, LYP2, PTPN8, PTPN22.5, PTPN22.6, PTPN22
Positive Sample:Jurkat, Mouse spleen
Cellular Localization:Cytoplasm.
Calculated MW:92kDa
Observed MW:107kDa

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Purification MethodAffinity purification
Gene ID26191
RRIDAB_2760915
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PTPN22 Rabbit pAb (CAB1406) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
Product ImageImmunofluorescence analysis of C6 cells using PTPN22 Rabbit pAb (CAB1406) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of U-2 OS cells using PTPN22 Rabbit pAb (CAB1406) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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