Cell Biology Antibodies 13

PRX Rabbit Polyclonal Antibody (CAB17744)

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SKU:
CAB17744
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CMT4F, PRX
Research Use:
Cell Biology
Frequently bought together:

Description

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PRX Antibody (CAB17744)

The PRX Antibody (CAB17744) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the PRX protein, this antibody enables the detection and analysis of PRX in various cell types, making it an essential component for studies in oxidative stress, cell biology, and disease research.PRX, also known as peroxiredoxin, is a key antioxidant enzyme that helps protect cells from oxidative damage and maintains cellular redox balance.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PRX Antibody
SKU:CAB17744
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:LGAR ARVG GEGA EEQP PGAE RTFC LSLP DVEL SPSG GNHA EYQV AEGE GEAG HKLK VRLP RFGL VRAK EGAE EGEK AKSP KLRL PRVG FSQS EMVT GEGS P
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CMT4F, PRX
Positive Sample:U-251MG, A-549
Cellular Localization:Anchoring Junction, Cytoplasm, Nucleus, Plasma Membrane.
Calculated MW:155kDa
Observed MW:155kDa

This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

Purification MethodAffinity purification
Gene ID57716
RRIDAB_2771853
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PRX Rabbit pAb (CAB17744) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunofluorescence analysis of C6 cells using PRX Rabbit pAb (CAB17744) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of U-2 OS cells using PRX Rabbit pAb (CAB17744) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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