Epigenetics & Nuclear Signaling Antibodies 5

PNN Rabbit Polyclonal Antibody (CAB16954)

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SKU:
CAB16954
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Rat
Synonyms:
DRS, DRSP, SDK3, memA, PNN
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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PNN Antibody (CAB16954)

The PNN Antibody (CAB16954) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody is highly specific to human samples and has been validated for use in applications such as Western blotting. By targeting the PNN protein, this antibody allows for detection and analysis in various cell types, making it ideal for studies in neuroscience and neurology.PNN, or perineuronal nets, are specialized extracellular matrix structures found around certain neurons in the brain. They play a crucial role in regulating synaptic plasticity, neuronal excitability, and neuroprotection.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.

Product Name:PNN Antibody
SKU:CAB16954
Size:20μL, 100μL
Reactivity:Human, Rat
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MAVA VRTL QEQL EKAK ESLK NVDE NIRK LTGR DPND VRPI QARL LALS GPGG GRGR GSLL LRRG FSDS GGGP PAKQ RDLE GAVS RLGG ERRT RRES RQES
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:DRS, DRSP, SDK3, memA, PNN
Positive Sample:LO2, HeLa, PC-12
Cellular Localization:Cell-Cell Junction, Desmosome, Nuclear Speck, Plasma Membrane.
Calculated MW:82kDa
Observed MW:130kDa

Enables RNA binding activity. Predicted to be involved in cell adhesion and mRNA splicing, via spliceosome. Predicted to act upstream of or within cell-cell adhesion. Located in nuclear speck. Part of catalytic step 2 spliceosome. Colocalizes with exon-exon junction complex.

Purification MethodAffinity purification
Gene ID5411
RRIDAB_2771727
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PNN Rabbit pAb (CAB16954) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
Product ImageWestern blot analysis of various lysates using PNN Rabbit pAb (CAB16954) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 120s.
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