Metabolism Antibodies 2

PNLIP Rabbit Polyclonal Antibody (CAB6396)

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SKU:
CAB6396
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
Reactivity:
Human, Mouse, Rat
Synonyms:
PL, PTL, PNLIPD, PNLIP
Research Use:
Metabolism
Frequently bought together:

Description

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PNLIP Antibody (CAB6396)

The PNLIP Antibody (CAB6396) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific to PNLIP and is validated for use in various applications, including Western blot and immunohistochemistry.PNLIP plays a crucial role in lipid metabolism, breaking down triglycerides into fatty acids and monoglycerides for absorption in the small intestine. Dysregulation of PNLIP activity has been linked to disorders such as pancreatitis and obesity, making it a target of interest in metabolic research.

This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PNLIP Antibody
SKU:CAB6396
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:IGHS LGAH AAGE AGRR TNGT IGRI TGLD PAEP CFQG TPEL VRLD PSDA KFVD VIHT DGAP IVPN LGFG MSQV VGHL DFFP NGGV EMPG CKKN ILSQ IVDI DGIW EGTR DFAA CNHL RSYK YYTD SIVN PDGF AGFP CASY NVFT ANKC FPCP SGGC PQMG HYAD RYPG KTND VGQK FYLD TGDA SNFA RWRY KVSV TLSG KKVT GHIL VSLF GNKG NSKQ YEIF KGTL KPDS THSN EFDS DVDV GDLQ MVKF IWYN NVIN PTLP RVGA SKII VETN VGKQ FNFC SPET VREE VLLT LTPC
Tested Applications:WB ELISA IF-P
Recommended Dilution:
WB1:500 - 1:2000
IF-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PL, PTL, PNLIPD, PNLIP
Positive Sample:Mouse liver, Mouse pancreas
Cellular Localization:Secreted.
Calculated MW:51kDa
Observed MW:55kDa

This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea.

Purification MethodAffinity purification
Gene ID5406
RRIDAB_2766998
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using PNLIP Rabbit pAb (CAB6396) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
Product ImageImmunofluorescence analysis of paraffin-embedded human pancreas using PNLIP Rabbit pAb (CAB6396) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.Perform high pressure antigen retrieval with 0.01 M citrate buffer (pH 6.0) prior to IF staining.
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