Signal Transduction Antibodies 3

PDC Rabbit Polyclonal Antibody (CAB8447)

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SKU:
CAB8447
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
PHD, MEKA, PhLP, PhLOP, PDC
Research Use:
Signal Transduction
Frequently bought together:

Description

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PDC Antibody (CAB8447)

The PDC Antibody (CAB8447) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody is raised in rabbits and is highly reactive with human samples, making it an ideal choice for experiments involving Phosducin in Western blot applications.Phosducin is known for its involvement in regulating G protein signaling and neurotransmitter release, making it a key player in processes related to neuronal function and communication. By targeting the Phosducin protein, researchers can gain valuable insights into its function and contribution to cellular signaling pathways.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PDC Antibody
SKU:CAB8447
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MEEA KSQS LEED FEGQ ATHT GPKG VIND WRKF KLES QDSD SIPP SKKE ILRQ MSSP QSRN GKDS KERV SRKM SIQE YELI HKEK EDEN CLRK YRRQ CMQD MHQK LSFG PRYG FVYE LETG KQFL ETIE KELK ITTI VVHI YEDG IKGC DALN SSLT CLAA EYPI VKFC KIKA SNTG AGDR FSLD VLPT LLIY KGGE LISN FISV AEQF AEEF FAGD VESF LNEY GLLP EREV HVLE HTKI EEED VE
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PHD, MEKA, PhLP, PhLOP, PDC
Positive Sample:LO2, 22Rv1, 293T
Cellular Localization:Cell Projection, Cytoplasm, Nucleus, Nucleus, Photoreceptor Inner Segment, Cilium, Cytosol, Photoreceptor Outer Segment.
Calculated MW:28kDa
Observed MW:36kDa

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

Purification MethodAffinity purification
Gene ID5132
RRIDAB_2770820
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using PDC Rabbit pAb (CAB8447) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat retina using PDC Rabbit pAb (CAB8447) at dilution of 1:200 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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