Signal Transduction Antibodies 1

Anti-PEBP4 Antibody (CAB14485)

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SKU:
CAB14485

Description

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Antibody Name:Anti-PEBP4 Antibody
Antibody SKU:CAB14485
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 23-120 of human PEBP4 (NP_659399.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Mouse
Positive Samples:Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 23-120 of human PEBP4 (NP_659399.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DEDE NSPC AHEA LLDE DTLF CQGL EVFY PELG NIGC KVVP DCNN YRQK ITSW MEPI VKFP GAVD GATY ILVM VDPD APSR AEPR QRFW RHWL VTDI KG
Gene ID:157310
Uniprot:Q96S96
Cellular Location:Lysosome
Calculated MW:25kDa
Observed MW:26kDa
Synonyms:PEBP4, CORK-1, CORK1, GWTM1933, HEL-S-300, PEBP-4, PRO4408, hPEBP4
Background:
UniProt Protein Function:PEBP4: Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization. Belongs to the phosphatidylethanolamine-binding protein family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Lipid-binding; Secreted

Chromosomal Location of Human Ortholog: 8p21.3

Molecular Function:protein binding

NCBI Summary:The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008]
UniProt Code:Q96S96
NCBI GenInfo Identifier:143811436
NCBI Gene ID:157310
NCBI Accession:Q96S96.3
UniProt Secondary Accession:Q96S96,Q5EVA1, Q8WW74,
UniProt Related Accession:Q96S96
Molecular Weight:25,733 Da
NCBI Full Name:Phosphatidylethanolamine-binding protein 4
NCBI Synonym Full Names:phosphatidylethanolamine binding protein 4
NCBI Official Symbol:PEBP4  
NCBI Official Synonym Symbols:CORK1; CORK-1; PEBP-4; hPEBP4; PRO4408; GWTM1933; HEL-S-300  
NCBI Protein Information:phosphatidylethanolamine-binding protein 4
UniProt Protein Name:Phosphatidylethanolamine-binding protein 4
UniProt Synonym Protein Names:Protein cousin-of-RKIP 1
Protein Family:Phosphatidylethanolamine-binding protein
UniProt Gene Name:PEBP4  
UniProt Entry Name:PEBP4_HUMAN
Anti-PEBP4 Antibody (CAB14485)Western blot analysis of extracts of mouse lung, using PEBP4 antibody (CAB14485) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
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Additional Information

Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
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