Signal Transduction Antibodies 1
Anti-PEBP4 Antibody (CAB14485)
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- SKU:
- CAB14485
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-PEBP4 Antibody |
| Antibody SKU: | CAB14485 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-120 of human PEBP4 (NP_659399.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-120 of human PEBP4 (NP_659399.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DEDE NSPC AHEA LLDE DTLF CQGL EVFY PELG NIGC KVVP DCNN YRQK ITSW MEPI VKFP GAVD GATY ILVM VDPD APSR AEPR QRFW RHWL VTDI KG |
| Gene ID: | 157310 |
| Uniprot: | Q96S96 |
| Cellular Location: | Lysosome |
| Calculated MW: | 25kDa |
| Observed MW: | 26kDa |
| Synonyms: | PEBP4, CORK-1, CORK1, GWTM1933, HEL-S-300, PEBP-4, PRO4408, hPEBP4 |
| Background: |
| UniProt Protein Function: | PEBP4: Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization. Belongs to the phosphatidylethanolamine-binding protein family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Lipid-binding; Secreted Chromosomal Location of Human Ortholog: 8p21.3 Molecular Function:protein binding |
| NCBI Summary: | The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008] |
| UniProt Code: | Q96S96 |
| NCBI GenInfo Identifier: | 143811436 |
| NCBI Gene ID: | 157310 |
| NCBI Accession: | Q96S96.3 |
| UniProt Secondary Accession: | Q96S96,Q5EVA1, Q8WW74, |
| UniProt Related Accession: | Q96S96 |
| Molecular Weight: | 25,733 Da |
| NCBI Full Name: | Phosphatidylethanolamine-binding protein 4 |
| NCBI Synonym Full Names: | phosphatidylethanolamine binding protein 4 |
| NCBI Official Symbol: | PEBP4 |
| NCBI Official Synonym Symbols: | CORK1; CORK-1; PEBP-4; hPEBP4; PRO4408; GWTM1933; HEL-S-300 |
| NCBI Protein Information: | phosphatidylethanolamine-binding protein 4 |
| UniProt Protein Name: | Phosphatidylethanolamine-binding protein 4 |
| UniProt Synonym Protein Names: | Protein cousin-of-RKIP 1 |
| Protein Family: | Phosphatidylethanolamine-binding protein |
| UniProt Gene Name: | PEBP4 |
| UniProt Entry Name: | PEBP4_HUMAN |
 | Western blot analysis of extracts of mouse lung, using PEBP4 antibody (CAB14485) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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