Developmental Biology

PAX2 Rabbit Polyclonal Antibody (CAB3067)

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SKU:
CAB3067
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Developmental Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
FSGS7, PAPRS, PAX-2, PAX2
Research Use:
Developmental Biology
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Description

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PAX2 Antibody (CAB3067)

The PAX2 Antibody (CAB3067) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PAX2 protein, this antibody enables accurate detection and analysis in different cell types, making it an essential asset for studies in developmental biology and oncology research.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PAX2 Antibody
SKU:CAB3067
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:TPDG AGTG VTAP GHTI VPST ASPP VSSA SNDP VGSY SING ILGI PRSN GEKR KRDE VEVY TDPA HIRG GGGL HLVW TLRD VSEG SVPN GDSQ SGVD SLRK HLRA DTFT QQQL EALD RVFE RPSY PDVF QASE HIKS EQGN EYSL PALT PGLD EVKS SLSA STNP ELGS NVS
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:100 - 1:500
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:FSGS7, PAPRS, PAX-2, PAX2
Positive Sample:PC-12, Jurkat
Cellular Localization:Nucleus.
Calculated MW:45kDa
Observed MW:47kDa

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID5076
RRIDAB_2764870
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using PAX2 Rabbit pAb (CAB3067) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 180s.
Product ImageImmunofluorescence analysis of A549 cells using PAX2 Rabbit pAb (CAB3067). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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