Epigenetics & Nuclear Signaling Antibodies 2

PARP2 Rabbit Polyclonal Antibody (CAB16475)

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SKU:
CAB16475
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Mouse, Rat
Synonyms:
ARTD2, ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2, PARP2
Research Use:
Epigenetics and Nuclear Signaling
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Description

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PARP2 Antibody (CAB16475)

The PARP2 Antibody (CAB16475) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot and immunohistochemistry applications.PARP2 plays a crucial role in the repair of DNA damage, making it an essential target for studies related to cancer, neurodegenerative diseases, and other conditions linked to genomic instability. By detecting and analyzing PARP2 expression levels in various cell types, researchers can gain insights into the mechanisms underlying DNA repair processes and the potential implications for disease development.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:PARP2 Antibody
SKU:CAB16475
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:FADM SSKS ANYC FASR LKNT GLLL LSEV ALGQ CNEL LEAN PKAE GLLQ GKHS TKGL GKMA PSSA HFVT LNGS TVPL GPAS DTGI LNPD GYTL NYNE YIVY N
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ARTD2, ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2, PARP2
Positive Sample:Mouse testis, Rat testis
Cellular Localization:Nucleus.
Calculated MW:66kDa
Observed MW:66kDa

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

Purification MethodAffinity purification
Gene ID10038
RRIDAB_2770793
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PARP2 Rabbit pAb (CAB16475) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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