Cell Death Antibodies 1

p70 S6 Kinase 1 Rabbit Polyclonal Antibody (CAB2190)

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SKU:
CAB2190
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
S6K, PS6K, S6K1, STK14A, p70-S6K, p70 S6KA, p70-alpha, S6K-beta-1, p70(S6K)-alpha, p70 S6 Kinase 1
Research Use:
Cell Death
Frequently bought together:

Description

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p70 S6 Kinase 1 Antibody (CAB2190)

The p70 S6 Kinase 1 Antibody (CAB2190) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to RPS6KB1, this antibody enables precise detection and analysis of the protein in a variety of cell types, making it an excellent choice for studies in molecular biology and cancer research.RPS6KB1, also known as ribosomal protein S6 kinase beta-1, is a critical player in signaling pathways that control protein synthesis and cell survival.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:p70 S6 Kinase 1 Antibody
SKU:CAB2190
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:SVKE KFSF EPKI RSPR RFIG SPRT PVSP VKFS PGDF WGRG ASAS TANP QTPV EYPM ETSG IEQM DVTM SGEA SAPL PIRQ PNSG PYKK QAFP MISK RPEH
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:S6K, PS6K, S6K1, STK14A, p70-S6K, p70 S6KA, p70-alpha, S6K-beta-1, p70(S6K)-alpha, p70 S6 Kinase 1
Positive Sample:Jurkat, 293T
Cellular Localization:Cell Junction, Cytoplasm, Mitochondrion Outer Membrane, Mitochondrion, Nucleus, Synapse, Synaptosome.
Calculated MW:59kDa
Observed MW:70kDa

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Purification MethodAffinity purification
Gene ID6198
RRIDAB_2749844
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using p70 S6 Kinase 1 Rabbit pAb (CAB2190) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human breast cancer using p70 S6 Kinase 1 1 Rabbit pAb (CAB2190) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunofluorescence analysis of NIH-3T3 cells using p70 S6 Kinase 1 1 Rabbit pAb (CAB2190) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of U-2 OS cells using p70 S6 Kinase 1 1 Rabbit pAb (CAB2190) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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