Cell Biology Antibodies 17
Purinergic Receptor P2Y6 Rabbit Monoclonal Antibody (CAB3708)
- SKU:
- CAB3708
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
- Antibody Type:
- Monoclonal Antibody
- Synonyms:
- P2Y6, Purinergic Receptor P2Y6
- Research Use:
- Cell Biology
Description
Purinergic Receptor P2Y6 Monoclonal Antibody (CAB3708)
The Purinergic Receptor P2Y6 Monoclonal Antibody (CAB3708) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit monoclonal cells, exhibits high specificity and sensitivity when detecting P2Y6 in human samples, making it a reliable choice for Western blot applications.P2Y6 is a G protein-coupled receptor that responds to extracellular nucleotides, playing a role in immune responses, inflammation, and cell proliferation. Its activation has been implicated in numerous diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
| Product Name: | Purinergic Receptor P2Y6 Monoclonal Antibody |
| SKU: | CAB3708 |
| Size: | 20μL, 100μL |
| Reactivity: | Human |
| Clone Number: | ARC0831 |
| Conjugate: | Unconjugated |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. | ||||
| Sequence: | VAQE RRGK AARM AVVV AAAF AISF LPFH ITKT AYLA VRST PGVP CTVL EAFA AAYK GTRP FASA NSVL DPIL FYFT QKKF RRRP HELL QKLT AKWQ RQGR | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
| ||||
| Synonyms: | P2Y6, Purinergic Receptor P2Y6 |
| Positive Sample: | A549, U-937, U-87MG |
| Cellular Localization: | Cell Membrane, Multi-Pass Membrane Protein. |
| Calculated MW: | 36kDa |
| Observed MW: | 42kDa |
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
| Purification Method | Affinity purification |
| Gene ID | 5031 |
| RRID | AB_2863126 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3. |
 | Western blot analysis of various lysates using Purinergic Receptor Purinergic Receptor P2Y6 Rabbit mAb (CAB3708) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s. |
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