Cell Death Antibodies 2

OPA1 Rabbit Polyclonal Antibody (CAB9833)

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SKU:
CAB9833
Product Type:
Antibody
Applications:
WB
Applications:
IF
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
NPG, NTG, MGM1, BERHS, largeG, MTDPS14, OPA1
Research Use:
Cell Death
Frequently bought together:

Description

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OPA1 Antibody (CAB9833)

The OPA1 Antibody (CAB9833) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to OPA1, this antibody allows for precise detection and analysis of the protein in various cell types, making it a versatile option for studies in mitochondrial biology and related diseases.OPA1, also known as optic atrophy 1 protein, plays a crucial role in maintaining mitochondrial function and integrity.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:OPA1 Antibody
SKU:CAB9833
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:SESD KHFR KVSD KEKI DQLQ EELL HTQL KYQR ILER LEKE NKEL RKLV LQKD DKGI HHRK LKKS LIDM YSEV LDVL SDYD ASYN TQDH LPRV VVVG DQSA GKTS VLEM IAQA RIFP RGSG EMMT RSPV KVTL SEGP HHVA LFKD SSRE FDLT KEED LAAL RHEI ELRM RKNV KEGC TVSP ETIS LNVK GPGL QRMV LVDL PGVI NTVT SGMA PDTK ETIF SISK AYMQ NPNA IILC IQDG SVDA ERSI VTDL VSQM DPHG RRTI FVLT KVDL AEKN VASP SRIQ QIIE GKLF PMKA LGYF AVVT GKGN SSES IEAI REYE EEFF QNSK LLKT SMLK AHQV TTRN LSLA VSDC FWKM VRES VEQQ ADSF KATR FNLE TEWK NNYP RLRE LDRN ELFE KAKN E
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:2000 - 1:8000
IF/ICC1:50 - 1:200
IHC-P1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NPG, NTG, MGM1, BERHS, largeG, MTDPS14, OPA1
Positive Sample:A-431, Mouse heart, Mouse brain, Rat brain, Rat heart
Cellular Localization:Mitochondrion Inner Membrane, Mitochondrion Intermembrane Space, Single-Pass Membrane Protein.
Calculated MW:112kDa
Observed MW:80-100kDa

The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness.

Purification MethodAffinity purification
Gene ID4976
RRIDAB_2770723
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using OPA1 Rabbit pAb (CAB9833) at 1:7000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human colon carcinoma tissue using OPA1 Rabbit pAb (CAB9833) at a dilution of 1:1000 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat heart tissue using OPA1 Rabbit pAb (CAB9833) at a dilution of 1:1000 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
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