Epigenetics & Nuclear Signaling Antibodies 1
Olig2 Rabbit Polyclonal Antibody (CAB12814)
- SKU:
- CAB12814
- Product Type:
- Antibody
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
- Reactivity:
- Human, Mouse, Rat
- Synonyms:
- BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19, Olig2
- Research Use:
- Epigenetics and Nuclear Signaling
Description
Olig2 Antibody (CAB12814)
The Olig2 Antibody (CAB12814) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in techniques such as Western blotting.Olig2 is a key player in the regulation of neural progenitor cells and is involved in various neurological disorders and brain tumors.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
| Product Name: | Olig2 Antibody |
| SKU: | CAB12814 |
| Size: | 20μL, 100μL |
| Reactivity: | Human, Mouse, Rat |
| Conjugate: | Unconjugated |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. | ||||||
| Sequence: | MDSD ASLV SSRP SSPE PDDL FLPA RSKG SSGS AFTG GTVS SSTP SDCP PELS AELR GAMG SAGA HPGD KLGG SGFK SSSS | ||||||
| Tested Applications: | WB IHC-P ELISA | ||||||
| Recommended Dilution: |
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| Synonyms: | BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19, Olig2 |
| Positive Sample: | U-87MG, C6 |
| Cellular Localization: | Cytoplasm, Nucleus. |
| Calculated MW: | 32kDa |
| Observed MW: | 35kDa |
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.
| Purification Method | Affinity purification |
| Gene ID | 10215 |
| RRID | AB_2759654 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using Olig2 Rabbit pAb (CAB12814) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s. |
 | Immunohistochemistry analysis of paraffin-embedded Rat brain using Olig2 Rabbit pAb (CAB12814) at dilution of 1:200 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
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