Cell Biology Antibodies 8

NRG4 Rabbit Polyclonal Antibody (CAB2599)

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SKU:
CAB2599
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
HRG4, NRG4
Research Use:
Cell Biology
Frequently bought together:

Description

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NRG4 Antibody (CAB2599)

The NRG4 Antibody (CAB2599) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.NRG4 is a biomarker associated with metabolic disorders, such as obesity and diabetes, as well as various cancers. Studies have shown that NRG4 is involved in regulating lipid metabolism, glucose homeostasis, and insulin sensitivity.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:NRG4 Antibody
SKU:CAB2599
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MPTD HEEP CGPS HKSF CLNG GLCY VIPT IPSP FCRC VENY TGAR CEEV FLPG SSIQ TKSN LFEA FVAL AVLV TLII GAFY FLCR KGHF QRAS SVQY DINL
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HRG4, NRG4
Positive Sample:Rat lung
Cellular Localization:Cell Membrane, Secreted, Single-Pass Type I Membrane Protein.
Calculated MW:13kDa
Observed MW:13kDa

The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).

Purification MethodAffinity purification
Gene ID145957
RRIDAB_2764484
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Rat lung, using NRG4 Rabbit pAb (CAB2599) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat brain using NRG4 Rabbit pAb (CAB2599) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse lung using NRG4 Rabbit pAb (CAB2599) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse brain using NRG4 Rabbit pAb (CAB2599) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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