The NR2E1/TLX Monoclonal Antibody (CAB8768) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity to human samples, making it ideal for use in a variety of applications such as immunofluorescence, immunohistochemistry, and flow cytometry.NR2E1, also known as Tailless (TLX), is a transcription factor that plays a crucial role in the regulation of neural stem cell self-renewal and differentiation. Its importance in neurogenesis and brain development has led to increased interest in studying its function and downstream signaling pathways.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
NR2E1/TLX Monoclonal Antibody
SKU:
CAB8768
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1295
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TLL, TLX, XTLL, NR2E1/TLX
Positive Sample:
SH-SY5Y, U-251MG, U-87MG, Mouse brain, Rat brain
Cellular Localization:
Nucleus.
Calculated MW:
43kDa
Observed MW:
43kDa
The protein encoded by this gene is an orphan receptor involved in retinal development. The encoded protein also regulates adult neural stem cell proliferation and may be involved in control of aggressive behavior. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
7101
RRID
AB_2863605
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using NR2E1/TLX Rabbit mAb (CAB8768) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
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