Epigenetics & Nuclear Signaling Antibodies 3

NKRF Rabbit Polyclonal Antibody (CAB4853)

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SKU:
CAB4853
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
NRF, ITBA4, NKRF
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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NKRF Antibody (CAB4853)

The NKRF Antibody (CAB4853) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications.NKRF, also known as NF-kappa-B-repressing factor, is a transcriptional regulator that modulates the activity of NF-kappa-B, a key player in the immune response. By targeting NKRF, researchers can gain insights into the mechanisms underlying inflammatory processes, autoimmune diseases, and cancer development.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:NKRF Antibody
SKU:CAB4853
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:YGTK KTSK HAAA DEAL KILQ KTQP TYPS VKSS QCHT GSSP RGSG KKKD IKDL VVYE NSSN PVCT LNDT AQFN RMTV EYVY ERMT GLRW KCKV ILES EVIA EAVG VKKT VKYE AAGE AVKT LKKT QPTV INNL KKGA VEDV ISRN EIQG RSAE EAYK QQIK EDNI GNQL LRKM GWTG GGLG KSGE GIRE PISV KEQH KREG LGLD VERV NKIA KRDI EQII RNYA RSES HTDL TFSR ELTN DERK QIHQ IAQK YGLK SKSH GVGH DRYL VVGR KRRK EDLL DQLK QEGQ VGHY ELVM PQAN
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NRF, ITBA4, NKRF
Positive Sample:U-87MG, A-549, Mouse brain, Mouse spleen, Mouse kidney, Rat brain
Cellular Localization:Nucleus, Nucleolus.
Calculated MW:78kDa
Observed MW:78kDa

This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID55922
RRIDAB_2765906
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using NKRF Rabbit pAb (CAB4853) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
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