Signal Transduction Antibodies 1

NGDN Rabbit Polyclonal Antibody (CAB14509)

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SKU:
CAB14509
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Rat
Synonyms:
NGD, LCP5, CANu1, lpd-2, C14orf120, NGDN
Research Use:
Signal Transduction
Frequently bought together:

Description

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NGDN Antibody (CAB14509)

The NGDN Antibody (CAB14509) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting.NGDN, or Noggin, is a secreted protein that plays a critical role in regulating the growth and development of nerve cells in the brain. Dysregulation of NGDN has been implicated in neurological disorders such as Alzheimer's disease, Parkinson's disease, and autism spectrum disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.

Product Name:NGDN Antibody
SKU:CAB14509
Size:20μL, 100μL
Reactivity:Human, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LMYL MDLT HLIL DKAS GGSL QGHD AVLR LVEI RTVL EKLR PLDQ KLKY QIDK LIKT AVTG SLSE NDPL RFKP HPSN MMSK LSSE DEEE DEAE DDQS EASG KKSV KGVS KKYV PPRL VPVH YDET EAER EKKR LERA KRRA LSSS VIRE L
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NGD, LCP5, CANu1, lpd-2, C14orf120, NGDN
Cellular Localization:Cell Projection, Chromosome, Cytoplasm, Nucleus, Axon, Centromere, Dendrite, Filopodium, Nucleolus.
Calculated MW:36kDa
Observed MW:RefertoFigures

Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).

Purification MethodAffinity purification
Gene ID25983
RRIDAB_2761383
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using NGDN Rabbit pAb (CAB14509) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
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