Epigenetics & Nuclear Signaling Antibodies 3

NFATC2 Rabbit Polyclonal Antibody (CAB14189)

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SKU:
CAB14189
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
JCOSL, NFAT1, NFATP, NFATC2
Research Use:
Epigenetics and Nuclear Signaling
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Description

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NFATC2 Antibody (CAB14189)

The NFATC2 Antibody (CAB14189) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high specificity and sensitivity for detecting NFATC2 in human samples, making it ideal for use in Western blot experiments. By targeting the NFATC2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it essential for studies in immunology, cancer research, and cell signaling pathways.NFATC2, also known as Nuclear Factor of Activated T cells 2, plays a crucial role in regulating gene expression in response to various stimuli, including immune activation and cellular stress.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:NFATC2 Antibody
SKU:CAB14189
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MNAP ERQP QPDG GDAP GHEP GGSP QDEL DFSI LFDY EYLN PNEE EPNA HKVA SPPS GPAY PDDV LDYG LKPY SPLA SLSG EPPG RFGE PDRV GPQK FLSA AKPA GASG LSPR IEIT PSHE LIQA VGPL RMRD AGLL VEQP PLAG VAAS PRFT LPVP GFEG YREP LCLS PASS GSSA SFIS DTFS PYTS PCVS PNNG GPDD LCPQ FQNI PAHY SPRT SPIM SPRT SLAE DSCL GRHS PVPR PASR SSSP GAKR RHSC AEAL VALP PGAS PQRS RSPS PQPS SHVA PQDH GSPA GYPP VAGS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:JCOSL, NFAT1, NFATP, NFATC2
Positive Sample:Jurkat, mouse thymus, mouse spleen, rat liver
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:100kDa
Observed MW:130kDa

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Purification MethodAffinity purification
Gene ID4773
RRIDAB_2761048
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using NFATC2 Rabbit pAb (CAB14189) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
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