Cell Biology Antibodies 6

MYOF Rabbit Polyclonal Antibody (CAB15427)

(No reviews yet) Write a Review
SKU:
CAB15427
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
HAE7, FER1L3, OF
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

MYOF Antibody (CAB15427)

The MYOF Antibody (CAB15427) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting MyoF in human samples, making it an invaluable asset for Western blot analyses.MyoF, also known as myogenic factor, plays a pivotal role in skeletal muscle development and function by regulating the expression of genes involved in muscle growth and differentiation. Dysregulation of MyoF has been linked to muscle disorders and neuromuscular diseases, making it an attractive target for therapeutic interventions aimed at treating these conditions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:MYOF Antibody
SKU:CAB15427
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MLRV IVES ASNI PKTK FGKP DPIV SVIF KDEK KKTK KVDN ELNP VWNE ILEF DLRG IPLD FSSS LGII VKDF ETIG QNKL IGTA TVAL KDLT GDQS RSLP YKLI SLLN EKGQ DTGA TIDL VIGY DPPS APHP NDLS GPSV PGMG GDGE EDEG DEDR LDNA VRGP GPKG PVGT VSEA QLAR RLTK VKNS RR
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HAE7, FER1L3, OF
Positive Sample:HeLa
Cellular Localization:Cell Membrane, Cytoplasmic Vesicle Membrane, Nucleus Membrane, Single-Pass Type Ii Membrane Protein.
Calculated MW:235kDa
Observed MW:250kDa

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

Purification MethodAffinity purification
Gene ID26509
RRIDAB_2762335
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type(WT) and MYOF knockout (KO) HeLa(KO) cells, using [KO Validated] MYOF Rabbit pAb (CAB15427) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
View AllClose

0 Reviews

View AllClose

Related Products