Epigenetics & Nuclear Signaling Antibodies 3

MYCBP Rabbit Polyclonal Antibody (CAB4623)

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SKU:
CAB4623
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
Synonyms:
AMY-1, MYCBP
Research Use:
Epigenetics and Nuclear Signaling
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Description

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MYCBP Antibody (CAB4623)

The MYCBP Antibody (CAB4623) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.Myc Binding Protein, also known as JPO1, interacts with the Myc oncogene to regulate gene expression and promote cell growth.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:MYCBP Antibody
SKU:CAB4623
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAHY KAAD SKRE QFRR YLEK SGVL DTLT KVLV ALYE EPEK PNSA LDFL KHHL GAAT PENP EIEL LRLE LAEM KEKY EAIV EENK KLKA KLAQ YEPP QEEK RAE
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:100 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:AMY-1, MYCBP
Positive Sample:A-549, K-562
Cellular Localization:Cytoplasm, Mitochondrion, Nucleus.
Calculated MW:12kDa
Observed MW:12kDa

The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene.

Purification MethodAffinity purification
Gene ID26292
RRIDAB_2765791
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using MYCBP Rabbit pAb (CAB4623) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human thyroid cancer using MYCBP Rabbit pAb (CAB4623) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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