Anti-Mouse IFNγ [H22] In Vivo Antibody - Ultra Low Endotoxin
- SKU:
- IVMB0034
- Product Type:
- In Vivo Monoclonal Antibody
- Clone:
- H22
- Protein:
- Interferon Gamma
- Isotype:
- Armenian Hamster IgG
- Reactivity:
- Mouse
- Synonyms:
- Immune Interferon
- Synonyms:
- Type II Interferon
- Synonyms:
- T Cell Interferon
- Synonyms:
- MAF
- Synonyms:
- IFNG
- Synonyms:
- IFG
- Synonyms:
- IFNy
- Research Area:
- Interferons
- Endotoxin Level:
- Ultra Low Endotoxin
- Host Species:
- Armenian Hamster
- Applications:
- ELISA
- Applications:
- IF
- Applications:
- IP
- Applications:
- Neutralizing
- Applications:
- WB
Description
system_update_altTechnical Datasheet
Product Name: | Anti-Mouse IFNγ [H22] In Vivo Antibody - Ultra Low Endotoxin |
Product Code: | IVMB0034 |
Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
Clone: | H22 |
Protein: | IFN-gamma |
Product Type: | Monoclonal Antibody |
Synonyms: | Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFNγ |
Isotype: | Armenian Hamster IgG |
Reactivity: | Mouse |
Immunogen: | Purified Recombinant Mouse IFN-gamma (>98%) |
Applications: | ELISA, IF, IP, N, WB |
Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
Endotoxin Level: | <0.5 EU/mg as determined by the LAL method |
Purity: | ≥98% monomer by analytical SEC >95% by SDS Page |
Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Applications: | ELISA, IF, IP, N, WB |
Recommended Usage: | WB The suggested concentration for this clone H22 antibody for use in western blotting is 0.5 µg/ml. |
Reactivity: | Mouse |
Host Species: | Armenian Hamster |
Specificity: | Armenian Hamster Anti-Mouse Interferon Gamma (IFN-gamma) (Clone H22) recognizes an epitope on Mouse IFN-gamma. This antibody was also pathogen tested and third-party certified by IDEXX BioReseach to meet the lowest mycoplasma specification and free of any viral pathogens of concern. |
Immunogen: | Purified Recombinant Mouse IFN-gamma (>98%) |
Concentration: | ≥ 5.0 mg/ml |
Endotoxin Level: | >0.5 EU/mg as determined by the LAL method |
Purity: | ≥98% monomer by analytical SEC >95% by SDS Page |
Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.3 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.4 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.5
Technical Datasheet: | View |
Protein: | IFN-gamma |
Ligand/Receptor: | IFN-γRα (CDw119) dimerized with IFN-γRβ (AF-1) |
Research Area: | Immunology |
Armenian Hamster IgG Isotype Control | |
---|---|
Clone | PIP |
Isotype | Armenian Hamster IgG1 |
Endotoxin Level | Ultra Low Endotoxin |
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