![Anti-Mouse IFNgamma [H22] In Vivo Antibody - Low Endotoxin (IVMB0033)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/78679/83861/anti-mouse-ifng-h22-in-vivo-antibody-low-endotoxin__91282__59950.1706545309.jpg?c=1?imbypass=on "Anti-Mouse IFNgamma [H22] In Vivo Antibody - Low Endotoxin (IVMB0033)")
Description
Anti-Mouse IFNgamma [H22] In Vivo Antibody - Low Endotoxin
Introducing the Anti-Mouse IFN-γ [H22] In Vivo Antibody - Low Endotoxin from Assay Genie, a highly specific monoclonal antibody designed for in vivo applications. This antibody targets the IFN-γ (Interferon gamma) protein, a crucial cytokine in immune response, making it ideal for research in immunology and related fields.
With a rat IgG1 isotype, it ensures high purity and low endotoxin levels (<1.0 EU/mg), perfect for ELISA, neutralization, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline for stability and efficacy. Enhance your research with this reliable and versatile antibody. IFN-γ is a critical cytokine in innate and adaptive immunity against viral, some bacterial, and protozoal infections. It is primarily produced by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. This antibody is perfect for studying immune responses, exploring cellular functions, and investigating cytokine signaling pathways.
| Product Name: | Anti-Mouse IFNgamma [H22] In Vivo Antibody - Low Endotoxin |
| Product Code: | IVMB0033 |
| Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
| Clone: | H22 |
| Protein: | Interferon Gamma |
| Product Type: | Monoclonal Antibody |
| Synonyms: | Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI |
| Isotype: | Armenian Hamster IgG |
| Reactivity: | Mouse |
| Immunogen: | Purified Recombinant Mouse IFN-γ (>98%) |
| Applications: | IP, N, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Applications: | IP, N, WB |
| Recommended Usage: | WB For Western blotting, the suggested use of clone H22 antibody is 0.6 µg/ml. |
| Reactivity: | Mouse |
| Host Species: | Armenian Hamster |
| Specificity: | Armenian Hamster Anti-Mouse Interferon-Gamma (IFN-γ) (Clone H22) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Immunogen: | Purified Recombinant Mouse IFN-γ (>98%) |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.4 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.5 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.6
| Datasheet: | View |
| Protein: | Interferon Gamma |
| Ligand/Receptor: | IFN-&gammalRα (CDw119) dimerized with IFN-γRβ (AF-1) |
| Research Area: | Immunology |
| Armenian Hamster IgG Isotype Control | |
|---|---|
| Clone | PIP |
| Isotype | Armenian Hamster IgG |
| Endotoxin Level | Low Endotoxin |
![Anti-Mouse IFNgamma [H22] In Vivo Antibody - Low Endotoxin (IVMB0033)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/78679/83861/anti-mouse-ifng-h22-in-vivo-antibody-low-endotoxin__91282__59950.1706545309.jpg?c=1 "Anti-Mouse IFNgamma [H22] In Vivo Antibody - Low Endotoxin (IVMB0033)")
![Anti-Mouse IFNgamma [H22] In Vivo Antibody - Ultra Low Endotoxin (IVMB0034)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/78680/83862/anti-mouse-ifng-h22-in-vivo-antibody-ultra-low-endotoxin__21469__11114.1706545309.jpg?c=1 "Anti-Mouse IFNgamma [H22] In Vivo Antibody - Ultra Low Endotoxin (IVMB0034)")
![Anti-Mouse IFNgamma [XMG1.2] In Vivo Antibody - Low Endotoxin (IVMB0022)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/78668/83850/anti-mouse-ifng-xmg1.2-in-vivo-antibody-low-endotoxin__65665__33033.1706545304.jpg?c=1 "Anti-Mouse IFNgamma [XMG1.2] In Vivo Antibody - Low Endotoxin (IVMB0022)")
