Anti-Mouse IFNγ [H22] In Vivo Antibody

Product Name:	Anti-Mouse IFNγ [H22] In Vivo Antibody - Low Endotoxin
Product Code:	IVMB0033
Size:	1mg, 5mg, 25mg, 50mg, 100mg
Clone:	H22
Protein:	Interferon Gamma
Product Type:	Monoclonal Antibody
Synonyms:	Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI
Isotype:	Armenian Hamster IgG
Reactivity:	Mouse
Immunogen:	Purified Recombinant Mouse IFN-γ (>98%)
Applications:	IP, N, WB
Formulation:	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Endotoxin Level:	< 1.0 EU/mg as determined by the LAL method
Purity:	≥95% monomer by analytical SEC >95% by SDS Page
Preparation:	Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:	Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Product Code	Product Name	Endotoxin Level
IVMB0033	Anti-Mouse IFNγ [H22] In Vivo Antibody - Low Endotoxin	Low
IVMB0034	Anti-Mouse IFNγ [H22] In Vivo Antibody - Ultra Low Endotoxin	Ultra Low

Applications:	IP, N, WB
Recommended Usage:	WB For Western blotting, the suggested use of clone H22 antibody is 0.6 µg/ml.
Reactivity:	Mouse

Host Species:	Armenian Hamster
Specificity:	Armenian Hamster Anti-Mouse Interferon-Gamma (IFN-γ) (Clone H22) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Immunogen:	Purified Recombinant Mouse IFN-γ (>98%)
Concentration:	≥ 5.0 mg/ml
Endotoxin Level:	< 1.0 EU/mg as determined by the LAL method
Purity:	≥95% monomer by analytical SEC >95% by SDS Page
Formulation:	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Preparation:	Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:	Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.4 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.5 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.6

Technical Datasheet:	View
Protein:	Interferon Gamma
Ligand/Receptor:	IFN-&gammalRα (CDw119) dimerized with IFN-γRβ (AF-1)
Research Area:	Immunology

Armenian Hamster IgG Isotype Control
Clone	PIP
Isotype	Armenian Hamster IgG
Endotoxin Level	Low Endotoxin

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