Cell Biology Antibodies 8

MMP25 Rabbit Polyclonal Antibody (CAB3032)

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SKU:
CAB3032
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
MMP20, MMPL1, MMP-25, MMP20A, MT6MMP, MTMMP6, MT-MMP6, MT6-MMP, MT-MMP 6, MMP25
Research Use:
Cell Biology
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Description

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MMP25 Antibody (CAB3032)

The MMP25 Antibody (CAB3032) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the MMP25 protein, researchers can effectively detect and analyze MMP25 expression in various cell types, providing valuable insights into its role in processes such as tumor metastasis and tissue repair.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MMP25 Antibody
SKU:CAB3032
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:SPRP ARLH RFWE GLPA QVRV VQAA YARH RDGR ILLF SGPQ FWVF QDRQ LEGG ARPL TELG LPPG EEVD AVFS WPQN GKTY LVRG RQYW RYDE AAAR PDPG YPRD LSLW EGAP PSPD DVTV SNAG DTYF FKGA HYWR FPKN SIKT EPDA PQPM GPNW LDCP APSS GPRA PRPP KATP VSET CDCQ CELN QAA
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MMP20, MMPL1, MMP-25, MMP20A, MT6MMP, MTMMP6, MT-MMP6, MT6-MMP, MT-MMP 6, MMP25
Positive Sample:K-562, BT-474
Cellular Localization:Cell Membrane, Extracellular Side, Gpi-Anchor, Lipid-Anchor, Secreted, Extracellular Matrix, Extracellular Space.
Calculated MW:63kDa
Observed MW:70kDa

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.

Purification MethodAffinity purification
Gene ID64386
RRIDAB_2764838
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using MMP25 Rabbit pAb (CAB3032) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product ImageImmunofluorescence analysis of C6 cells using MMP25 Rabbit pAb (CAB3032) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of L929 cells using MMP25 Rabbit pAb (CAB3032) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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