Cell Biology Antibodies 10

MATK Rabbit Polyclonal Antibody (CAB6651)

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SKU:
CAB6651
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CHK, CTK, HYL, Lsk, HYLTK, HHYLTK, MATK
Research Use:
Cell Biology
Frequently bought together:

Description

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MATK Antibody (CAB6651)

The MATK Antibody (CAB6651) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.MATK, also known as megakaryocyte-associated tyrosine kinase, plays a crucial role in various cellular processes, including cell migration, adhesion, and cytoskeletal rearrangement.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MATK Antibody
SKU:CAB6651
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:PEAL KHGK FTSK SDVW SFGV LLWE VFSY GRAP YPKM SLKE VSEA VEKG YRME PPEG CPGP VHVL MSSC WEAE PARR PPFR KLAE KLAR ELRS AGAP ASVS GQDA DGST SPRS QEP
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CHK, CTK, HYL, Lsk, HYLTK, HHYLTK, MATK
Positive Sample:THP-1
Cellular Localization:Cytoplasm, Membrane.
Calculated MW:56kDa
Observed MW:56kDa

The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Purification MethodAffinity purification
Gene ID4145
RRIDAB_2767239
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from THP-1 cells, using MATK Rabbit pAb (CAB6651) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat kidney using MATK Rabbit pAb (CAB6651) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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